|Aliases:||Home to Brother Brit-Man and Spider-Gwen, Earth-14211|
|Debut appearance:||Excalibur Vol. 1 #44|
|Alan Davis, Jason Latour, Robbi Rodriguez|
| Spider-Gwen Vol. 1|
Spider-Gwen Vol. 2
Earth-65 is the home reality of Gwen Stacy who was bitten by a radioactive spider, becoming Spider-Woman.
Instead of Peter Parker, Gwen Stacy was bitten by a radioactive spider and used her powers to become Spider-Woman and make New York a safer place.
Peter Parker went on to become the Lizard, in an effort to become "special" like Gwen. Peter died in a battle with Spider-Woman in her arms. The police see this and incriminate Spider-Woman for Peter's death as Captain George Stacy orders for her arrest.
After George was rescued by Spider-Woman from Aleksei Sytsevich, she was held at gunpoint and she revealed his identity to him, somewhat changing his views on Spider-Woman.
When alone, George asked Gwen to give up being Spider-Woman, but she declined and saved him from the Vulture soon after and then defeated Frank Castle in a fight.